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钱国良

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钱国良 老师


 

1个人简介

钱国良,男,19812月生,现为南京农业大学植物保护学院教授,博士生导师。主讲本科生植物保护通论课程。2013年入选教育部新世纪优秀人才支持计划;2012年受聘为南京农业大学钟山学术新秀。从事植物病害生物防治研究,目前的工作聚集于生防溶杆菌(细菌)中小分子抗菌物质的鉴定、生物合成及其调控机制解析。

近几年来,主持或参与国家级、省部级科研项目7项,包括主持国家自然科学基金3项、国家973计划1项(核心骨干)、主持教育部新世纪人才计划1项。以第一作者和通讯作者在本领域的国际学术刊物上共计发表SCI论文21篇,包括Journal of the American Chemical Society (IF: 10), Organic Letters (IF:6.7), Molecular Microbiology, Journal of Proteome Research, Molecular Plant Pathology, Applied and Environmental Microbiology, Applied Microbiology and Biotechnology, Phytopathology, Microbial BiotechnologyBiological Control。现为《植物病理学报》编委(2015-2018年),美国植物病理学会、美国微生物学会、美国化学学会、中国植物病理学会和江苏省植物病理学会会员。

2)教育经历(按时间倒排序)

20049-200912月,南京农业大学,植物保护学院植物病理系,硕博连读/农学博士,导师刘凤权教授

20009-20046月,南京农业大学,植物保护学院,本科/农学学士

3)工作经历(科研与学术工作经历,按时间倒序排序)

201612-至今,南京农业大学,植物保护学院植物病理系,教授/博导。主要从事植物病害生物防治与分子植物病原细菌学研究

20159-20169月,美国怀俄明大学(University of Wyoming)访问学者,从事细菌第二信使c-di-GMP的调控机制研究 (导师/合作者:Prof. Mark Gomelsky

20121-201612月,南京农业大学,植物保护学院植物病理系,副教授/硕导。主要从事植物病害生物防治与分子植物病原细菌学研究

201010-201012月,美国内布拉斯加林肯大学,访问学者。主要从事新型生防细菌-产酶溶杆菌抗真菌卵菌活性物质HSAF的生物合成机理研究

200912-2012 1 月,南京农业大学,植物保护学院植物病理系,讲师。主要从事植物病害生物防治与分子植物病原细菌学研究

4)教学和科研获奖

2013年入选教育部新世纪优秀人才支持计划

2012年受聘为南京农业大学钟山学术新秀

2012-2013学年第一学期南京农业大学教学质量综合评价优秀

2012-2013学年第二学期南京农业大学教学质量综合评价优秀

2012年获南京农业大学第十届青年教师授课比赛三等奖

2014年南京农业大学优秀学生教育管理工作者

2014年南京农业大学第三期中青年干部培训班优秀学员

2014年南京农业大学教育思想大讨论征文三等奖

2014年作为班主任所在的植保113班获得校“十佳班级”称号

2014年作为班主任所在的植保113班获得江苏省“先进班级”荣誉

5)主要学术任职

2015-2018 《植物病理学报》编委

200912-至今 中国植物病理学会会员,美国植物病理学会、美国化学学会和微生物学会会员

 

7)论文发表(#表示共同第一作者;*表示通论作者

1.         LiLi Lou#, Guoliang Qian#Yunxun Xie, Jiliang Hang, Haotong Chen, Kathia Zaleta-Rivera, Yaoyao Li, Yuemao Shen, Patrick H Dussault, Fengquan Liu*, Liangcheng Du*. 2011. Biosynthesis of HSAF, a tetramic acid-containing macrolactam from Lysobacter enzymogenes. Journal of the American Chemical Society 133 (4): 643-645. IF: 10.0

2.         Yangyang Zhao#, Guoliang Qian#, Yonghao Ye, Stephen Wright, Hantong Chen, Yuemao Shen, Fengquan Liu* and Liangcheng Du*. 2016. Heterocyclic aromatic N-oxidation in the biosynthesis of phenazine antibiotics from Lysobacter antibioticus. Organic Letters 18: 2495-2498. IF: 6.7

3.         Zhenhe Su, Hongfu Chen, Ping Wang, Simon Tombosa, Liangcheng Du, Yong Han, Yuemao Shen, Guoliang Qian*, Fengquan Liu*. 2017. 4-hydroxybenzoic acid is a diffusible factor that connects metabolic shikimate pathway to the biosynthesis of a unique antifungal metabolite in Lysobacter enzymogenes. Molecular Microbiology 104: 163-178.

4.         Guoliang Qian, Yulan Wang, Yiru Liu, Feifei Xu, Ya-Wen He, Liangcheng Du, Vittorio Venturi, Jiaqin Fan, Baishi Hu, Fengquan Liu*. 2013. Lysobacter enzymogenes uses two distinct cell-cell signaling systems for differential regulation of secondary-metabolite biosynthesis and colony morphology. Applied and Environmental Microbiology 79:6604-6616.

5.         Yuan Chen, Jing Xia, Zhenhe Su, Gaoge Xu, Mark Gomelsky, Guoliang Qian*, Fengquan Liu*. 2017. The regulator of type IV pili synthesis, PilR, from Lysobacter controls antifungal antibiotic production via a c-di-GMP pathway. Applied and Environmental Microbiology e03397-16.

6.         Guoliang Qian, Feifei Xu, Vittorio Venturi, Liangcheng Du, Fengquan Liu*. 2014. Roles of a solo LuxR in the biological control agent Lysobacter enzymogenes strain OH11. Phytopathology 104 (3): 224-231. Highlight in Phytopathology website.

7.          Ping Wang, Hongfu Chen, Guoliang Qian*, Fengquan Liu*. 2017. LetR is a TetR family transcription factor from Lysobacter controlling antifungal antibiotic biosynthesis. Applied Microbiology and Biotechnology 101: 3273-3282.

8.         Yansheng Wang, Yuxin Zhao, Juan Zhang, Yangyang Zhao, Yan Shen, Zhenhe Su, Gaoge Xu, Liangcheng Du, Justin M. Huffman, Vittorio Venturi, Guoliang Qian* and Fengquan Liu*. 2014. Transcriptomic analysis reveals new regulatory roles of Clp signaling in secondary metabolite biosynthesis and surface motility in Lysobacter enzymogenes OH11. Applied Microbiology and Biotechnology 98: 9009-9020.

9.         Gaoge Xu, Yuxin Zhao, Liangcheng Du, Guoliang Qian*, Fengquan Liu*. 2015. Hfq regulates antibacterial antibiotic biosynthesis and extracellular lytic-enzyme production in Lysobacter enzymogenes OH11. Microbial Biotechnology 8: 499-509.

10.     Huiyong Xu, Hongfu Chen, Yuemao Shen, Liangcheng Du, Shan-Ho Chou, Hongxia Liu, Guoliang Qian*, Fengquan Liu*. 2016. Direct regulation of extracellular chitinase production by the transcription factor LeClp in Lysobacter enzymogenes OH11. Phytopathology 106: 971-977.

11.     Gaoge Xu, Xiaofeng Shi, Ruping Wang, Huiyong Xu, Liangcheng Du, Shan-Ho Chou, Hongxia Liu, Youzhou Liu, Guoliang Qian*, Fengquan Liu*. 2016. Insights into the distinct cooperation between the transcription factor Clp and LeDSF signaling in the regulation of antifungal factors in Lysobacter enzymogenes OH11. Biological control DOI: 10.1016/j.biocontrol.2016.08.006, online.

12.     Ruping Wang, Huiyong Xu, Liangcheng Du, Shan-Ho Chou, Hongxia Liu, Youzhou Liu, Fengquan Liu*, Guoliang Qian*. 2016. A TonB-dependent receptor regulates antifungal HSAF biosynthesis in Lysobacter. Scientific Reports 6: 26881.

13.     Juan Zhang, Liangcheng Du, Fengquan Liu, Feifei Xu, Baishi Hu, Vittorio Venturi, Guoliang Qian*. 2014. Involvement of both PKS and NRPS in antibacterial activity in Lysobacter enzymogenes OH11. FEMS Microbiology Letters 355: 170-176.

14.     Xue Zhou#, Guoliang Qian#, Yuan Chen, Liangcheng Du, Fengquan Liu, Gary Y Yuen. 2015. PilG is involved in the regulation of twitching motility and antifungal antibiotic biosynthesis in the biological control agent Lysobacter enzymogenes. Phytopathology 105: 1318-1324.

15.     Guoliang Qian, Yansheng Wang, Dongyu Qian, Jiaqin Fan, Baishi Hu, Fengquan Liu*. 2012. Selection of available suicide vectors for gene mutagenesis using chiA (a chitinase encoding gene) as a new reporter and primary functional analysis of chiA in Lysobacter enzymogenes strain OH11. World Journal of Microbiology and Biotechnology 28: 549-557.

16.     Mimi Zhou, Danyu Shen, Gaoge Xu, Fengquan Liu, Guoliang Qian*. 2017. ChpA controls twitching motility and broadly affects gene expression in the biological control agent Lysobacter enzymogenes. Current Microbiology 74: 566-574.

17.     Guoliang Qian, Baishi Hu, Yinghua Jiang, Fengquan Liu*. 2009. Identification and characterization of Lysobacter enzymogenes as a biological control agent against some fungal pathogens. Agricultural Sciences in China 8(1): 68-75.

18.     Guoliang Qian, Yijing Zhou, Yancun Zhao, Zhiwei Song, Suyan Wang, Jiaqin Fan, Baishi Hu, Vittorio Venturi, Fengquan Liu*. 2013. Proteomic analysis reveals novel extracellular virulence-associated proteins and functions regulated by the Diffusible Signal Factor (DSF) in Xanthomonas oryzae pv. oryzicola. Journal of Proteome Research 12: 3327-3341.

19.     Guoliang Qian, Chunhui Liu, Guichun Wu, Fangqun, Yin, Yancun Zhao, Yijing Zhou, Yanbing Zhang, Zhiwei Song, Jiaqin Fan, Baishi Hu, Fengquan Liu*. 2013. AsnB, regulated by diffusible signal factor and global regulator Clp, is involved in aspartate metabolism, resistance to oxidative stress and virulence in Xanthomonas oryzae pv. oryzicola. Molecular plant pathology 14(2): 145-157.

20.     Guoliang Qian, Yanbing Zhang, Yijing Zhou, Chunhui Liu, Yancun Zhao, Zhiwei Song, Jiaqin Fan, Baishi Hu, Fengquan Liu*. 2012. epv, encoding a hypothetical protein, is regulated by DSF-mediating quorum sensing as well as global regulator Clp and is required for optimal virulence in Xanthomonas oryzae pv. oryzicola. Phytopathology 102 (9): 841-847.